Uwe Klinge Selected Research

Foreign-Body Reaction

1/2021	A peritoneal defect covered by intraperitoneal mesh prosthesis effects an increased and distinctive foreign body reaction in a minipig model.
1/2015	Polyvinylidene Fluoride as a Suture Material: Evaluation of Comet Tail-Like Infiltrate and Foreign Body Granuloma.
4/2010	Absence of circulating aldosterone attenuates foreign body reaction around surgical sutures.
12/2009	Foreign body reaction in vaginally eroded and noneroded polypropylene suburethral slings in the female: a case series.
4/2007	Polymeric meshes induce zonal regulation of matrix metalloproteinase-2 gene expression by macrophages and fibroblasts.
3/2006	Is there a risk of infertility after inguinal mesh repair? Experimental studies in the pig and the rabbit.

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Uwe Klinge Research Topics

Disease

11	Hernia (Hernias) 11/2013 - 01/2002
10	Cicatrix (Scar) 09/2013 - 03/2002
8	Inflammation (Inflammations) 01/2015 - 11/2002
8	Inguinal Hernia (Direct Inguinal Hernia) 07/2014 - 01/2002
6	Neoplasms (Cancer) 04/2022 - 01/2007
6	Granuloma 01/2022 - 04/2010
6	Foreign-Body Reaction 01/2021 - 03/2006
6	Incisional Hernia 01/2021 - 03/2002
4	Foreign Bodies (Foreign Body) 01/2022 - 04/2010
4	Foreign-Body Granuloma (Granuloma, Foreign Body) 01/2015 - 04/2007
3	Vascular Remodeling 02/2013 - 08/2009
3	Stress Urinary Incontinence 05/2012 - 05/2007
3	Endotoxemia 10/2005 - 09/2004
2	Necrosis 01/2017 - 11/2002
2	Fibrosis (Cirrhosis) 08/2009 - 07/2007
2	Ischemia 03/2009 - 11/2002
2	Infections 03/2005 - 02/2004
2	Contracture 12/2004 - 03/2003
1	Klatskin Tumor 04/2022
1	Colorectal Neoplasms (Colorectal Cancer) 10/2021
1	Acute Liver Failure (Fulminant Hepatic Failure) 01/2021
1	Cholestasis 04/2019
1	Wounds and Injuries (Trauma) 01/2018
1	Hemorrhage 01/2018
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 10/2014
1	Neoplasm Metastasis (Metastasis) 06/2014
1	Reperfusion Injury 01/2014
1	Body Weight (Weight, Body) 01/2014
1	Abdominal Hernia (Abdominal Hernias) 04/2013
1	Bronchogenic Carcinoma 07/2011
1	Sexually Transmitted Diseases (Sexually Transmitted Disease) 08/2010
1	Kidney Diseases (Kidney Disease) 08/2009
1	Cardiomegaly (Heart Hypertrophy) 08/2009
1	Thrombosis (Thrombus) 08/2009
1	Hodgkin Disease (Hodgkin's Disease) 06/2009

Drug/Important Bio-Agent (IBA)

18	CollagenIBA 01/2020 - 01/2002
6	Polypropylenes (Polypropylene)IBA 01/2017 - 02/2004
6	Proteins (Proteins, Gene)FDA Link 05/2010 - 03/2002
6	Matrix Metalloproteinases (MMPs)IBA 04/2010 - 01/2002
4	polyvinylidene fluoride (PVDF)IBA 01/2020 - 07/2007
4	PolymersIBA 01/2015 - 04/2007
4	Biological ProductsIBA 05/2010 - 02/2004
4	Collagen Type I (Type I Collagen)IBA 04/2010 - 02/2004
3	Biocompatible Materials (Biomaterials)IBA 01/2021 - 12/2011
3	IronIBA 07/2014 - 08/2010
3	Messenger RNA (mRNA)IBA 09/2006 - 01/2002
3	Collagen Type III (Type III Collagen)IBA 09/2006 - 01/2002
3	ZincIBA 10/2005 - 09/2004
2	Biomarkers (Surrogate Marker)IBA 04/2022 - 06/2014
2	Indicators and Reagents (Reagents)IBA 01/2017 - 02/2012
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2014 - 04/2010
2	AldosteroneIBA 02/2013 - 04/2010
2	Capsules (Microcapsules)IBA 07/2009 - 03/2003
2	SiliconesIBA 09/2007 - 03/2003
2	Gentamicins (Gentamicin)FDA LinkGeneric 07/2007 - 03/2005
2	CytokinesIBA 10/2005 - 09/2004
2	Escherichia coli endotoxinIBA 02/2005 - 09/2004
2	RNA (Ribonucleic Acid)IBA 04/2002 - 01/2002
1	N-formyl-13-dihydrocarminomycin (NFD)IBA 04/2022
1	6-propylchromone-2-carboxylic acid (PCCA)IBA 04/2022
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2021
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 04/2019
1	Fibrinogen (Factor I)FDA Link 01/2018
1	CarbonatesIBA 01/2017
1	Urethane (Ethyl Carbamate)IBA 01/2017
1	Meloxicam (Mobic)FDA LinkGeneric 01/2014
1	Icodextrin (Extraneal)FDA Link 09/2013
1	Spironolactone (Aldactone)FDA LinkGeneric 12/2011
1	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2011
1	Dehydroepiandrosterone (DHEA)IBA 09/2011
1	FluoridesIBA 01/2011
1	ferric oxide (iron oxide)IBA 08/2010
1	OxidesIBA 08/2010
1	MineralocorticoidsIBA 04/2010
1	Cold Shock Proteins and PeptidesIBA 04/2010
1	deoxyuridine triphosphateIBA 04/2010
1	Y-Box-Binding Protein 1IBA 04/2010
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 04/2010
1	Type II Tumor Necrosis Factor ReceptorsIBA 04/2010
1	growth arrest-specific protein 6IBA 08/2009
1	Desoxycorticosterone Acetate (DOCA)FDA Link 08/2009
1	Fibronectins (Fibronectin)IBA 08/2009
1	Interleukin-6 (Interleukin 6)IBA 08/2009
1	CalciumIBA 06/2009
1	Death-Associated Protein KinasesIBA 06/2009
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 06/2009
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 06/2009

Therapy/Procedure

5	Therapeutics 06/2014 - 09/2004
4	Surgical Mesh 01/2022 - 04/2002
4	Sutures (Suture) 01/2017 - 03/2009
3	Laparotomy 01/2021 - 11/2002
3	Suburethral Slings (Tension-Free Vaginal Tape) 05/2012 - 05/2007
2	Prostheses and Implants (Prosthesis) 01/2021 - 02/2004
2	Ligation 01/2021 - 10/2014
2	Herniorrhaphy 09/2006 - 03/2006
1	Hepatectomy 04/2019
1	Warm Ischemia 01/2014
1	Operative Surgical Procedures 11/2013
1	Euthanasia (Mercy Killing) 05/2010
1	Adrenalectomy 04/2010